ADDITIONAL INFORMATION FOR THIS PRODUCT

Actoplus Met
is a combination of two oral diabetes medicines that help control blood sugar levels.
Actoplus Met is for people with type 2 diabetes who do not use daily insulin injections. This medication is not for treating type 1 diabetes.

Drug Uses
It is important to use your doses of Actoplus Met along with your main meals.
A regular use of this medicine will ensure that you will receive the expected beneficial results. During your therapy with this diabetes medication, you ought to undergo regular blood examinations in order to make sure that your treatment is working properly. Adjacent liver / kidney clinical evaluations may also be necessary. Some patients may have to take vitamin B12 supplements during their therapy with this drug.
You should acquire a personalized dosing schedule from your healthcare provider. They will know the exact amount of Actoplus Met that you ought to employ on a regular basis in order to achieve the maximum beneficial results from your therapy with this product.

Missed dose
Take the missed dose as soon as you remember (be sure to take the medicine with food). If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Overdose
Seek emergency medical attention if you think you have used too much of this medicine. You may have signs of low blood sugar, such as hunger, headache, confusion, irritability, drowsiness, weakness, dizziness, tremors, sweating, fast heartbeat, seizure (convulsions), fainting, or coma. An overdose of Actoplus Met may cause a life-threatening condition called lactic acidosis. Get emergency medical help if you have any of these symptoms of lactic acidosis: weakness, increasing sleepiness, slow heart rate, cold feeling, muscle pain, shortness of breath, stomach pain, feeling light-headed, and fainting.

Possible Side Effects
Get emergency medical help if you have any of these symptoms of lactic acidosis: weakness, increasing sleepiness, slow heart rate, cold feeling, muscle pain, shortness of breath, stomach pain, feeling light-headed, and fainting. Stop using Actoplus Met and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:
* feeling short of breath, even with mild exertion;
* swelling or rapid weight gain; or
* nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious Actoplus Met side effects may include:
* sneezing, runny nose, cough or other signs of a cold;
* dizziness;
* headache;
* mild nausea, vomiting, diarrhea, stomach pain; or
* joint or muscle pain.

Precautions
Patients who are suffering from kidney disorder and those who have diabetic ketoacidosis should not be allowed to start using Actoplus Met. Patients who have to undergo CT scan or x-ray clinical evaluations during their therapy with this drug will have to discontinue using this clinical remedy for a short period of time.
The presence of certain medical conditions may interfere with the patient's ability to start using Actoplus Met. For example, patients who are suffering from heart disease (congestive heart failure), stroke, heart attack, eye problems (due to untreated diabetes) and so on, will have to be prescribed an alternative therapy option for their condition. The safety of this medicine in the case of nursing or pregnant mothers has not yet been determined. Elderly individuals and young adolescents are known to be more sensitive to developing the more severe side effects of Actoplus Met.

Storage
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.